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2015 Fiscal Year Final Research Report

Aging related progression of Kakurehiman(normal weight obesity) worsen subjects of Met-s and life style related diseases

Research Project

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Project/Area Number 25350855
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Applied health science
Research InstitutionTokai University

Principal Investigator

NISHIZAKI Yasuhiro  東海大学, 医学部, 教授 (80237693)

Co-Investigator(Kenkyū-buntansha) ISHII Naoaki  東海大学, 医学部, 教授 (60096196)
Project Period (FY) 2013-04-01 – 2016-03-31
Keywords筋肉過少 / 内臓脂肪 / メタボリック症候群 / 生活習慣病 / 脂肪肝
Outline of Final Research Achievements

Normal BMI with higher body fat is so-called “kakure-himan” as the same meaning of normal weight obesity (NWO). In our study, body fat percentage (BFP) was measured using Impedance and DXA methods. Control group contains Normal BMI (18.5-24.9) with normal BFP (less than 20% in men and 25% in women). NWO group contains normal BMI with higher BFP (more than 20% in men and 25% in women). Obesity group contains Higher BMI (greater than 25.0) with higher BFP. Parameters associated with Met-S, lifestyle related diseases and arterial sclerosis were analyzed. NWO was recognized in 42% of men and in 60% of women, and percentages of the population were increased along to age. The serum levels of TG, FFA, UA, PWV were higher, while adiponectin was lower in NOW in contrst with control but some of that showed no difference between obesity group. These result suggest that kakure-himan, which could be a major risk for metabolic syndrome, lifestyle related diseases and arterial sclerosis.

Free Research Field

応用健康科学

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Published: 2017-05-10  

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