Development and validation of the real-time quantification of cerebral blood flow using an arterial spin labeling MRI

2016 Fiscal Year Final Research Report

• Project/Area Number: 25351003
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Brain biometrics
• Research Institution: National Institute of Information and Communications Technology
• Principal Investigator: Toyoda Hiroshi 国立研究開発法人情報通信研究機構, 脳情報通信融合研究センター脳情報通信融合研究室, 主任研究員 (10558084)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: MRI / 脳血流量

Outline of Final Research Achievements

We have developed a novel real-time measurement technique for quantitating cerebral blood flow using an arterial spin labeling method. Compared to the BOLD signal measurement, which is commonly used as a functional MRI method, the arterial spin labeling method generally requires more measurement time to image whole brain functions. In this study, high-speed MR imaging of cerebral blood flow was conducted by applying a parallel imaging technique to the arterial spin labeling method. To parallelize the imaging, we used a simultaneous multi-slice imaging technique with multi-band excitation RF pulses. Because it is less prone to magnetic susceptibility artifacts, the proposed imaging method may be used to investigate areas in the brain that were difficult to image using conventional BOLD functional MRI techniques.

Free Research Field

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