Synthesis of spherical micelles using irreversible photoreactions as a driving force of molecular self-assembly

2017 Fiscal Year Final Research Report

• Project/Area Number: 25390003
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Nanostructural chemistry
• Research Institution: Toyohashi University of Technology
• Principal Investigator: Yoshida Eri 豊橋技術科学大学, 工学(系)研究科(研究院), 准教授 (60263175)
• Project Period (FY): 2013-04-01 – 2018-03-31
• Keywords: 自己組織化 / ミセル形成 / 不可逆的光反応 / 光分解 / 光転位 / 光オニウム塩形成 / 光重合 / ブロック共重合体

Outline of Final Research Achievements

A novel micelle formation was established using “irreversible” photoreactions as a driving force of molecular self-assembly. The photolysis, photorearrangement, coupled with photo salt formation served as a driving force of the self-assembly of diblock copolymers to produce nanosized micelles through a change in situ from the nonamphiphilic copolymers into the amphiphilic ones. The photopolymerization also induced the self-assembly of an amphiphilic diblock copolymer to provide microsized giant vesicles. The vesicles had some morphologies of spherical micelles, spherical vesicles, worm-like vesicles, and a bilayer sheet, depending on the composition of the monomer units. The giant vesicles had several similarities to biomembrane not only in their size and structure but also in the stimuli-responsive behavior and membrane permeability, suggesting that the vesicles consisting of the diblock copolymer could be a possible artificial model of the biomembrane.

Free Research Field

ラジカル重合化学