Elucidation of formation mechanism of luminescent nanoparticles prepared by laser ablation in liquid and their application in biomedical engineering

2015 Fiscal Year Final Research Report

• Project/Area Number: 25390014
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Nanomaterials chemistry
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: Wada Hiroyuki 東京工業大学, 総合理工学研究科(研究院), 准教授 (00422527)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: アップコンバージョン / 蛍光体 / ナノ粒子 / レーザー / がん治療

Outline of Final Research Achievements

Upconversion nanoparticles were prepared by laser ablation in liquid, which was irradiation with focused laser beam on material in water. Experiment using cancer cells indicated that they were useful for cancer therapy, which was photodynamic therapy (PDT). In the case of normal PDT, it is difficult to cure large or deep cancer. However, this study showed that PDT with using upconversion nanoparticles and near-infrared light, which is transparent for a living body, was likely to solve the problem.

Free Research Field

光材料化学