2015 Fiscal Year Final Research Report
Study on liquid-liquid transtion of protein hydaration water by collective dynamics and liquid strcuture analysis
| Project/Area Number |
25390130
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Quantum beam science
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| Research Institution | Fukuoka University |
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Principal Investigator |
Yoshida Koji 福岡大学, 理学部, 助教 (00309890)
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| Co-Investigator(Renkei-kenkyūsha) |
YAMAGUCHI TOSHIO 福岡大学, 理学部, 教授 (70158111)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | タンパク質 / 水和 / X線回折 / 中性子散乱 |
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| Outline of Final Research Achievements |
Collective dynamics and structure of hydration water for hydrated proteins and polypeptides were investigated by neutron and X-ray scatterings in the temperature range of 298 - 180 K. Hydration structure of proteins and amino acids confined in mesoporous silica and nano-water domain formed in ionic liquid-water mixture. The relation between protein dynamics and water was clarified and the water role in protein function was discussed.
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| Free Research Field |
溶液化学
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