2015 Fiscal Year Final Research Report
Chemical Evolutionary Model for Homochirality Growth Conducted by Oligopeptides
| Project/Area Number |
25400526
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Geochemistry/Cosmochemistry
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| Research Institution | Naruto University of Education |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | ホモキラリティー / オリゴペプチド / 分別 / エピ化 / 立体特異的縮合 |
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| Outline of Final Research Achievements |
Linear and cyclic alanine dipeptides were irradiated in solution or as solid state by gamma rays (1-24 kGy). The resulted reaction solutions were analyzed by means of HPLC equipped with achiral or chiral columns. Linear L-Ala-L-Ala epimerized faster (reaction rate constant: 0.017kGy-1) than D-Ala-L-Ala (0.0033kGy-1) in 1mM solutions. This suggests that such reaction conditions are not suited for accumulation of homochiral peptides. However, the results in the reactions using cyclic dipeptides showed heterochiral peptides epimerizes faster than homochiral peptides.
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| Free Research Field |
アストロバイロジー
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