Development of addition reaction of an E-H bond (E = main group elements having lone pair electrons) to alkynes catalyzed by an iron complex

2016 Fiscal Year Final Research Report

• Project/Area Number: 25410073
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Inorganic chemistry
• Research Institution: Osaka City University
• Principal Investigator: ITAZAKI Masumi 大阪市立大学, 大学院理学研究科, 講師 (60382032)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 鉄触媒 / ヒドロホスフィン化 / アルキン / インジウム / ヒドロシリル化 / ニトリル

Outline of Final Research Achievements

Iron complex-catalyzed regioselective single hydrophosphination of terminal arylalkyne with secondary phosphine was achieved. Unsymmetric 1,2-bis(phosphino)ethanes with different phosphino groups were obtained by using our catalytic systems. The structures of obtained vinylphosphine, unsymmetric 1,2-bis(phosphino)ethane, and iron catalyst precursors were confirmed by single crystal X-ray diffraction studies. In addition, Selective double hydrosilylation was achieved by using tertiary and secondary silanes with an excess amount of an organonitrile (RC≡N; R = alkyl, aryl) in the presence of a catalytic amount of triirondodecacarbonyl [Fe3(CO)12] and indium trichloride (InCl3). This reaction was also catalyzed by an iron complex containing indium trihalide [Fe(MeCN)6][Fe(CO)4(InCl3)2], prepared by the reaction of Fe3(CO)12 with InCl3. This is a novel report of the combination of a transition-metal complex and an indium source in organic synthesis.

Free Research Field

有機金属化学