Investigation on highly stereoselective preparation of organic molecules by means of photochemical activation

2015 Fiscal Year Final Research Report

• Project/Area Number: 25410105
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Synthetic chemistry
• Research Institution: Hokkaido University
• Principal Investigator: Arai Noriyoshi 北海道大学, 工学(系)研究科(研究院), 准教授 (80282721)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 有機合成化学 / 光反応 / 不斉合成 / 分子触媒 / 立体選択的合成

Outline of Final Research Achievements

It is an important research area to develop new methods for preparation of one of mirror image compounds (chiral compound) selectively. There is growing demand for such technology especially in pharmaceutical chemistry. We investigated on creation of a novel and original molecular photo catalyst, which makes it possible to build up complex compounds hardly accessible by conventional methods. We made a synthetic plan for the photo catalyst starting from readily available commercial chemicals, to succeed in preparation of the novel catalyst. We estimated the performance of the catalyst, to find the catalyst shows acceptable level of selective synthesis of chiral compounds, though there remained room for improvement. We are going to make further progress by modification of the molecular structure of the catalyst.

Free Research Field

有機合成化学