Development of the reactions with hydrogen based on hydride-accepting ability of organic cations

2016 Fiscal Year Final Research Report

• Project/Area Number: 25410108
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Synthetic chemistry
• Research Institution: Akita University
• Principal Investigator: SEINO Hidetake 秋田大学, 教育文化学部, 准教授 (50292751)
• Co-Investigator(Renkei-kenkyūsha): YOSHIE Naoko 東京大学, 生産技術研究所, 教授 (20224678)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 水素 / カチオン性複素環 / 錯体触媒 / 有機ヒドリド供与体 / ヒドロゲナーゼ / メタン生成 / 酸化還元反応

Outline of Final Research Achievements

Catalytic cleavage of hydrogen into proton and hydride followed by transfer of the hydride to cationic nitrogen-heterocycles was investigated. Organic products in this reaction system were stable under ambient conditions, but in the presence of catalysts could serve as organic hydride reagents to generate hydrogen gas via protonation or to reduce other organic molecules. One carbon unit was activated toward nucleophiles by composing a cationic heterocyclic system, and hydride transfer to this unit enabled advance of the reduction-level under mild conditions. This reaction is relevant to some steps in methanogenetic pathways utilizing hydrogen to reduce carbon dioxide with the aid of organic coenzymes.

Free Research Field

有機金属化学