2015 Fiscal Year Final Research Report
Stereoselective synthesis of alkenes using new Julia-type reagents
| Project/Area Number |
25410111
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Gifu University |
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Principal Investigator |
Ando Kaori 岐阜大学, 工学部, 教授 (70211018)
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| Co-Investigator(Renkei-kenkyūsha) |
OKA NATSUHISA 岐阜大学, 工学部, 准教授 (50401229)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | シス‐オレフィン / Julia-Kocienski reaction / アルケン合成 / 立体選択的 |
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| Outline of Final Research Achievements |
Although Julia-Kocienski reaction is a efficient tool for direct trans-alkene synthesis via metalated tetrazolylsulfones with aldehydes, cis-selective reagents are also needed. In this study, we developed a practical methylenation reation for aldehydes and ketones using new Julia-type reagents. Based on this results, we also found cis selective reaction for the synthesis of 1,3-dienes.
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| Free Research Field |
有機合成化学
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