2016 Fiscal Year Final Research Report
Development of new analysis protocols for identification and imaging of molecules in tissues
| Project/Area Number |
25410143
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
|
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| Research Institution | Seikei University (2014-2016)
Shimane University (2013) |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | 質量イメージング / 表面科学 / TOF-SIMS / 多変量解析 / 近接場赤外顕微鏡 |
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| Outline of Final Research Achievements |
Time-of-flight secondary ion mass spectrometry (TOF-SIMS) is a powerful analysis method because it provides detailed chemical images with high spatial resolution approximately 100 nm. However, it is often difficult to interpret TOF-SIMS data, especially for the analysis of unknown materials in multicomponent samples, due to complex spectrum information. New analysis protocols for identification and imaging of molecules in complex samples using TOF-SIMS and near-field infrared microscopy, which also provides chemical mapping, have been developed.
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| Free Research Field |
表面科学
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