Evaluation of novel medical devices developed by rapid formation of apatite layer on polymer substrate

2015 Fiscal Year Final Research Report

• Project/Area Number: 25420736
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Composite materials/Surface and interface engineering
• Research Institution: Sophia University
• Principal Investigator: ITATANI Kiyoshi 上智大学, 理工学部, 教授 (90129784)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: ポリエーテルエーテルケトン / 真空紫外光照射 / 表面改質 / マイクロ波加熱 / 水酸アパタイト / シランカップリング / 接着強化

Outline of Final Research Achievements

Rapid formation of biocompatible hydroxyapatite (Ca10(PO4)6(OH)2; HAp) layer on the polyetheretherketone (PEEK) substrate for a spinal fusion implant was examined. The process in this research included: (i) the surface modification of PEEK through the vacuum ultraviolet (VUV) irradiation (wavelength: 172 nm) or acid treatment, (ii) the immersion of surface-modified PEEK substrate into the HAp-dissolved solution (the dissolution of HAp powder into the de-ionized water with bubbling of CO2 gas at room temperature for 1 h), and (iii) the microwave heating at 100 ～ 140°C for 10 min to form HAp layer on the PEEK substrate.

Free Research Field

無機材料化学