2015 Fiscal Year Final Research Report
Awareness and attention in animal models of blindsight and spatial neglect
| Project/Area Number |
25430022
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neurophysiology / General neuroscience
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| Research Institution | National Institute for Physiological Sciences |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 視覚的気づき / 視覚的注意 / 盲視 / サリエンシー |
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| Outline of Final Research Achievements |
The aim of this research is to establish an animal model of spatial neglect. For this purpose, we made a lesion in the right superior temporal gyrus and evaluated their behavior with a target-selection task and eye-tracking. We found that neglect-like behavior was sustained for more than 1 month after the lesion. Thus we conclude that we established an animal model of spatial neglect. We also measured BOLD activity of the same monkeys before and after the lesion and found that the functional connectivity within the attention network is reduced and recovered, which was correlated with behavioral markers of spatial neglect after the lesion.
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| Free Research Field |
神経生理学
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