2015 Fiscal Year Final Research Report
Study of the central olfactory projection with genetic methods
| Project/Area Number |
25430045
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | National Institute of Genetics |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 神経回路形成 |
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| Outline of Final Research Achievements |
Conditional KO mice for target axon guidance signaling were made. With proper activity of the Cre recombinase, these mice showed abnormal phenotype in the axon guidance. However, two mice lines which express Cre recombinase in the olfactory bulb could not show enough activity to induce abnormal network formation in the central olfactory system. The tTA/tetO system also did not work well in the central olfactory projection.
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| Free Research Field |
神経発生
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