2015 Fiscal Year Final Research Report
| Project/Area Number |
25440175
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | University of Hyogo (2014-2015)
Tokushima Bunri University (2013) |
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Principal Investigator |
Okada Ryuichi 兵庫県立大学, 環境人間学部, 研究員 (20423006)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 脳 |
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| Outline of Final Research Achievements |
To examine neural mechanisms underlying memory formation, the activities of a mushroom body output neuron, PE1 neuron, was analyzed because this neuron shows a learning-related plasticity. However, it is still unknown whether and when PE1 changes its responses during the acquisition period. Using chronic recording from PE1 of a learning bee, we analyzed the spontaneous activity of PE1 between acquisition trials. The spectrum analysis for spontaneous activity showed that the peak of power spectrum of PE1 was shifted to the lower frequency along acquisition trials, suggesting that the inhibition of PE1 spiking activity became stronger than before learning. Next, to reveal inhibitory synaptic connections about PE1, we performed immuno-staining against GABA, iono-, and metabotropic GABA receptors. Immunohistology suggested that PE1 has no GABA-receptors, and thus an indirect neural control might be dominant in an inhibitory connection to PE1.
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| Free Research Field |
神経行動学
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