Searching genomic region participating adaptation to environment

2016 Fiscal Year Final Research Report

• Project/Area Number: 25440254
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Physical anthropology
• Research Institution: Tohoku University
• Principal Investigator: DANJOH Inaho 東北大学, 東北メディカル・メガバンク機構, 講師 (30415228)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 南米 / 先住民族 / ゲノム / コピー数多型 / SNP / 適応

Outline of Final Research Achievements

Amerinds, indigenous people in South America, are Mongoloid originated from Eurasian continents. During the migration path from Eurasian continent to South American continent approx. twelve thousand years ago, they have adapted to harsh environments; mountainous area height over 40,000 meters, or lowland where people take poisonous crops for staple. These life styles suggest that people have been underwent some adaptive selection. Analysis of genomic polymorphisms relating to environmental adaptations may reveal migration path of ancestors of Amerinds during prehistoric era. As a result of analysis, we identified several candidate SNPs relating to acclimatization to altitude and detoxification.

Free Research Field

ゲノム科学