Elucidation of diversity and function of bacterial photosensor

2015 Fiscal Year Final Research Report

• Project/Area Number: 25450113
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Applied microbiology
• Research Institution: Nihon University
• Principal Investigator: TAKANO Hideaki 日本大学, 生物資源科学部, 講師 (50385994)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 光センサー / LitR / カロテノイド / 非光合成細菌

Outline of Final Research Achievements

LitR family serves as a transcriptional regulator with photosensor function in a diverged non-phototrophic bacteria. We determined a three dimensional structure of the photosensor domain of Class I LitR. We also demonstrated the the biochemical properties of Class II LitR serving as a light-dependent repressor. We also revealed that TetR and MerR type regulator are involved in the light-dependent regulation in non-phototrophic bacteria. Our studies showed the novel molecular mechanism of photo-sensing mechanisms and the diversity in non-phototrophic bacteria.

Free Research Field

応用微生物学