2015 Fiscal Year Final Research Report
Study on the systems of improving meat qualities using cultured cell
| Project/Area Number |
25450285
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Aquatic bioproduction science
|
|---|
| Research Institution | Kinki University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
ANDO Masashi 近畿大学, 農学部, 教授 (80247965)
ITOH Tomohiro 近畿大学, 農学部, 准教授 (30435854)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Keywords | 細胞培養 / 繊維芽細胞 / 光老化 / 水銀 / メト化 |
|---|
| Outline of Final Research Achievements |
UV-induced photoaging effect was examined by human normal fibroblast. Plant extract X reduced the concentration of reactive oxygen species (ROS) in cells and p38MAPK activity which was activated by ROS.
The human colon cancer cell line Caco-2 was used as an intestinal absorption model. Mercury absorption inhibitors of various vegetables squeezing olution were screened. High mercury absorption inhibitory activity was observed in green pepper component of which molecular weight was around 3000.
It was found that 130 μmol/g of catechin and 1.3 μmol/g of sodium L-ascorbic acid had equivalents of inhibition effect of metmyoglobin formation, also suppression effects of lowering of pH and breaking strength by injection into the blood vessels of live fish.
|
| Free Research Field |
水産化学
|
