Effect of lysozyme polymorphism on antimicrobial activity and economic traits in Japanese quail

2015 Fiscal Year Final Research Report

• Project/Area Number: 25450399
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Animal production science
• Research Institution: Kagoshima University
• Principal Investigator: SHIMOGIRI Takeshi 鹿児島大学, 農水産獣医学域 農学系, 准教授 (40315403)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: リゾチーム / 家禽 / 抗菌タンパク質 / 生産形質 / 変異

Outline of Final Research Achievements

I investigated the effect of the variants of antimicrobial proteins on poultry production in this study. A polymorphism of the lysozyme gene, which was related to antimicrobial activity and hatchability, did not significantly affect the body weight at 6th weeks old, average egg weight and survival rate in Japanese quail. I tried to identify causal mutations of three variants of the chicken ovotransferrin gene. An Asp500Asn mutation was identified as a causal mutation between B and C variants. The B and C variants purified from egg white were not significantly different in antibacterial activity.

Free Research Field

動物遺伝学