Immunological study on bovine leukemia virus infection

2015 Fiscal Year Final Research Report

• Project/Area Number: 25450468
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Integrative animal science
• Research Institution: University of Miyazaki
• Principal Investigator: Norimine Junzo 宮崎大学, 産業動物リサーチセンター, 教授 (30627667)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 牛白血病 / 牛白血病ウイルス / 抵抗性遺伝子 / テトラマー / CD4T細胞

Outline of Final Research Achievements

Because approximately 70% of cattle infected with bovine leukemia virus remain healthy for their lives, it has been thought that there exist resistant genes exist against this disease. This study confirmed one of the resistant genes in both dairy and Japanese black cattle. The field study has demonstrated that cattle with the resistant gene could be utilized as a protectiveon wall for the infection. The investigator also developed the first immunological analytic tool, a bovine immunological “tetramer”, and is currently studying the resistant mechanisms using the tool.

Free Research Field

動物感染症学