2015 Fiscal Year Final Research Report
Understanding favorable trait of domestic animal and chronic disease of human based on epigenome engineering
| Project/Area Number |
25450472
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Integrative animal science
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| Research Institution | Meiji University |
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Principal Investigator |
Ohgane Jun 明治大学, 農学部, 准教授 (50313078)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | エピジェネティクス / エピゲノム改変 / 非コード（nc）RNA / 食肉形質 / 生活習慣病 |
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| Outline of Final Research Achievements |
DNA methylation analysis based on allelic methylation status has been established in the present project, and this enabled us to estimate ratios of particular cell types in tissues containing multiple cell types and heterogenous cultured cell populations. Moreover, a screening method to identify long non-coding RNAs related to epigenetic regulation of nearby genes has been established. Therefore, basic technology to perform epigenome engineering established in this project.
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| Free Research Field |
エピジェネティクス
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