2015 Fiscal Year Final Research Report
Quantitative evaluation of relative leaving group ability of hypervalent organobromanyl groups
| Project/Area Number |
25460016
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | The University of Tokyo (2014-2015)
The University of Tokushima (2013) |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 超原子価 / ハロゲン / 臭素 / 塩素 / キセノン / 脱離能 / ジアゾニウム |
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| Outline of Final Research Achievements |
The chemistry of hypervalent organobromine(III) and chlorine(III) compounds are still remained to be established. Therefore, we have investigated the driving force of their reactivity and its synthetic use in current organic synthesis. In this research project, we synthesized hypervalent organobromine(III) and chlorine(III) compounds suitable for kinetic study in order to evaluate the relative leaving group ability. Rate constants for unimolecular decomposition of these reagents found to be effective to compare leaving group ability of hypervalent haloganyl groups. In addition, during the above kinetic study, we found several new reactions which are useful for organic synthesis such as C-H activation of hydrocarbons with thermal decomposition of halonium ylide and aryl transfer reaction of diarylbromane(III) with iodoarenes.
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| Free Research Field |
有機合成化学
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