Asymmetric synthesis of helicenes by selective cycloaddition reactions of benzynes

2015 Fiscal Year Final Research Report

• Project/Area Number: 25460018
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Chemical pharmacy
• Research Institution: Osaka University
• Principal Investigator: IKAWA TAKASHI 大阪大学, 薬学研究科(研究院), 助教 (20453061)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: ベンザイン / ヘリセン / ノナフラート / 多環式芳香族化合物 / 連続反応 / フラン / 環化付加反応 / らせん

Outline of Final Research Achievements

Many scientists are now interested in helicenes, which is multiply fused benzenes at ortho positions, and they are working on various advanced researches using helicenes. However, it is still challenging to synthesize functionalized helicenes in short steps. In this research, the development of novel synthesis of helicenes using benzynes has been achieved. Additionally, novel helical molecules were successfully synthesized through new reaction using fused benzynes.

Free Research Field

有機化学