2016 Fiscal Year Final Research Report
Utility of herbal medicine for remission maintenance therapy of ulcerative colitis
| Project/Area Number |
25460123
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Natural medicines
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| Research Institution | Yamaguchi University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | 潰瘍性大腸炎 / 大建中湯 / dextran sulfate sodium |
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| Outline of Final Research Achievements |
We evaluated the effects of daikenchuto(DKT) on dextran sulfate sodium- (DSS-) induced ulcerative colitis(UC) mouse model. the colon lengths of DKT group were longer than those of the DSS group. the DKT group maintained significantly higher levels of serum hemoglobin. The DKT group exhibited significantly longer survival time than the DSS group. Our results indicate that DKT prevented inflammation in the colon, indicating its potential as a new therapeutic agent for UC.
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| Free Research Field |
消化器内科
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