2015 Fiscal Year Final Research Report
Pharmacokinetics and pharmacodynamics of novel antihyperuricemic drug.
| Project/Area Number |
25460187
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical pharmacy
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| Research Institution | Shiga University of Medical Science |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
Hira Daiki 滋賀医科大学, 医学部, 特任助教 (50636959)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 個別医療 / 薬物動態 |
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| Outline of Final Research Achievements |
The aim of the present study is to evaluate the influence of renal function and genetic variance of metabolic enzymes of febuxostat on pharmacokinetics and pharmacodynamics of febuxostat.
The population pharmacokinetic analysis from 84 patients shows that renal function and genetic variance of metabolic enzymes (UGT1A1 and CYP2C9) are not influence on pharmacokinetics and pharmacodynamics of febuxostat.
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| Free Research Field |
臨床薬学
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