• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2016 Fiscal Year Final Research Report

Molecular mechanisms of obesity- behavoral changes

Research Project

  • PDF
Project/Area Number 25460317
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Environmental physiology(including physical medicine and nutritional physiology)
Research InstitutionJichi Medical University (2014-2016)
Toho University (2013)

Principal Investigator

Takase Kenkichi  自治医科大学, 医学部, 教授 (80381474)

Project Period (FY) 2013-04-01 – 2017-03-31
Keywords肥満 / 行動 / MCH / HDAC
Outline of Final Research Achievements

Expressions of the HDAC family (HDAC 1 to 11) were examined in various brain regions and these results were published as a paper (Takase et al., 2013). In the process, the data on HDAC expressions of obese mice were accumulated. Furthermore, behavioral changes of mice deficient in MCH were quantitatively analyzed using statistical methods and these results were also published as a paper (Takase et al., 2014). We also quantitatively analyzed behavioral changes of obese mice and published there results as a paper (Takase et al., 2016). From the comparison of these data, we were able to obtain results supporting the validity of our research hypothesis. In addition, due to changes in the institution to which the applicant belongs, situations in which progress has been slightly delayed have also been improved. We are ready for comprehensive behavioral analysis of mice that manipulated HDAC expression and the analysis of gene expression changes in them.

Free Research Field

生物心理学

URL: 

Published: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi