2015 Fiscal Year Final Research Report
Studies on thrombophilia -deficiency and mutation of protein S-
| Project/Area Number |
25460398
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pathological medical chemistry
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| Research Institution | Nagasaki International University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KUMA Hiroyuki 長崎国際大学, 薬学部, 准教授 (40435136)
HATAE Hinako 長崎国際大学, 薬学部, 助教 (00551582)
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| Research Collaborator |
TSUDA Tomohide
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | プロテインS / 血栓性素因 / 深部静脈血栓症 / プロテインS比活性 |
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| Outline of Final Research Achievements |
In this study, we developed new assay system to be an effective screening tool for protein S (PS) deficiency. This assay named “PS specific activity test”was covered by insurance last year. When our new assay of PS specific activity was performed in blood samples of thrombosis patients, all of patients with low PS specific activity have genetic mutation. These data clearly show that protein S deficiency is one of major Japanese thrombophilia.
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| Free Research Field |
臨床検査医学
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