Pathological classification of the pituitary adenoma reflecting prognosis and therapeutic sensitivity.

2015 Fiscal Year Final Research Report

• Project/Area Number: 25460468
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Human pathology
• Research Institution: Okinaka Memorial Institute for Medical Research
• Principal Investigator: Inoshita Naoko 公益財団法人冲中記念成人病研究所, その他部局等, 研究員 (20300741)
• Co-Investigator(Kenkyū-buntansha): FUJII Takeshi 冲中記念成人病研究所, 研究員 (70228948)
• Co-Investigator(Renkei-kenkyūsha): YAMADA Shozo 冲中記念成人病研究所, 研究員 ; NISHIOKA Hiroshi 冲中記念成人病研究所, 研究員
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 下垂体腺腫 / 内分泌腫瘍 / 病理組織学 / 免疫染色

Outline of Final Research Achievements

Pituitary tumors are endocrine tumors. Half of these tumors cause a serious endocrine abnormalities, including Cushing's disease, gigantism, and acromegaly. The remaining half are non-functional tumors exhibiting severe neurological symptoms by the invasive and massive growth. Although pituitary tumor is a rare disease , we have the accumulation of many cases in our hospital, and continue to investigate clinical and pathological findings.
In the present study period, 1) was carried out re-classification of hormone staining negative non-functional adenomas, at the point of clinical findings, prognosis, and pathological study, and 2) clinicopathological study of pituitary adenomas with Cushing 's disease.

Free Research Field

内分泌病理学