The association among ferruginous body, uncoated fibers, asbestos and non-asbestos fibers in lung tissue

2015 Fiscal Year Final Research Report

• Project/Area Number: 25460821
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Hygiene and public health
• Research Institution: Aichi Medical University
• Principal Investigator: Eiji Shibata 愛知医科大学, 医学部, 教授 (90206128)
• Co-Investigator(Kenkyū-buntansha): SAKAKIBATA Yoko 愛知教育大学, 保健環境センター, 准教授 (90242891)
• Research Collaborator: SUZUKI Takayoshi ; HISANAGA Naomi ; SAKAI Kiyoshi
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 石綿 / 含鉄小体 / 石綿小体 / 位相差顕微鏡 / 肺内石綿濃度 / 剖検肺

Outline of Final Research Achievements

To demonstrate the correlations between the concentrations of ferruginous body as well as uncoated fiber both of which can be observed with phase-contrast microscope and the concentration of various inorganic fibers including asbestos which requires the observation with TEM or SEM, we measured those indices among Japanese and Korean cases. Though the concentration of ferruginous body in lung tissue is an important index of asbestos exposure, uncoated fibers observed with phase-contrast microscope might be another index especially in such cases with relatively low exposure due to their history of living in a general environment. However, to establish the reliability of uncoated fibers as an index of asbestos exposure, analysis with more cases and from various backgrounds must be carried out.

Free Research Field

労働衛生