2015 Fiscal Year Final Research Report
Anti-tumor effect of galectin 9 in hepatocell carcinoma:Basic study
| Project/Area Number |
25460998
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Gastroenterology
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| Research Institution | Kagawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TANI Joji 香川大学, 医学部, 助教 (00596075)
HIMOTO Takashi 香川県立保健医療大学, 保健医療学部, 教授 (20325343)
MIYOSHI Hisaaki 香川大学, 医学部附属病院, 助教 (40592316)
HIRASHIMA Mitsuomi 香川大学, 医学部, 研究員 (70109700)
YONEYAMA Hirohito 香川大学, 医学部附属病院, 助教 (80294750)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | Hepatocellular carcinoma / Gal-9 / microRNA / Cancer |
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| Outline of Final Research Achievements |
Anti-tumor effects of galectin-9 was detected in hepatocellular carcinoma cell induced the strong apoptosis through microRNA in vitro and in vivo（Int J Oncol. 2015 Jun;46(6):2419-30） In addition, the antitumor effect of galectin-9 was also detected in cholangiocarcinoma (Oncol Rep. 2015 Oct; 34 (4): 1761-70), gastric cancer (Oncol Rep. 2016 Feb; 35 (2): 851-60), gallbladder cancer(Int J Oncol. 2016 Mar; 48 (3): 1165-74).
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| Free Research Field |
Gastroenterology
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