2015 Fiscal Year Final Research Report
The establishment of treatment for pancreatic cancer using miRNA associated with stem cells related pancreatic cancer.
| Project/Area Number |
25461020
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Gastroenterology
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HAMADA Shin 東北大学, 医学系研究科, 助教 (20451560)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 膵癌 / EUS-FNA / miRNA |
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| Outline of Final Research Achievements |
We have obtained the histological sample of pancreatic cancer using Endoscopic ultrasonography-fine needle aspiration (EUS-FNA) and continued to make the genetic profile. The evaluation of expression of the marker associated with stem cells related pancreatic cancer was performed. However, we could not detect these markers. Since one of the causes not to detect these markers is that the amount of histological sample by EUS-FNA is very small, we continue to evaluate these markers using the histological samples acquired by operation. Furthermore, sensitivity test of anti cancer drug for pancreatic caner using histological sample acquired by EUS-FNA has been continued. We have compared the clinical information and surgical stage. The cell lines of resistance for anti-cancer drug were used for checking the genetic profile.
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| Free Research Field |
膵臓
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