2015 Fiscal Year Final Research Report
Evaluation of pulmonary circulation and right ventricular function by radiographic and invasive hemodynamic methods in patients with pulmonary hypertension
| Project/Area Number |
25461037
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular medicine
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
FUKUMOTO Yoshihiro 久留米大学, 医学部, 教授 (70363372)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 肺高血圧症 / 慢性血栓塞栓性肺高血圧症 / 右心機能 / 肺循環 / 心臓MRI / FDG-PET / 肺動脈バルーン形成術 |
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| Outline of Final Research Achievements |
The purpose of the present study was to evaluate both pulmonary circulation and right ventricular function by radiographic and invasive hemodynamic methods in patients with pulmonary hypertension. We have reported that （1）enhanced [18F] fluorodeoxyglucose accumulation in the right ventricular free wall predicts long-term prognosis of patients with pulmonary hypertension. We have also reported that in patients with chronic thromboembolic pulmonary hypertension, balloon pulmonary angioplasty improves (2) the severity of vortex flow in the main pulmonary artery assessed by four-dimensional magnetic resonance, (3) biventricular function and (4) systemic organ dysfunctions caused by right heart failure, associated with marked pulmonary hemodynamic improvements.
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| Free Research Field |
肺高血圧症
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