2015 Fiscal Year Final Research Report
Analysis of blood flow in the heart using MRI
Project/Area Number |
25461050
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Cardiovascular medicine
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Research Institution | Hamamatsu University School of Medicine |
Principal Investigator |
SAITOH TAKEJI 浜松医科大学, 医学部附属病院, 講師 (50402277)
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Co-Investigator(Kenkyū-buntansha) |
SATOH HIROSHI 浜松医科大学, 医学部附属病院, 講師 (30293632)
TAKEHARA YASUO 浜松医科大学, 医学部附属病院, 教授 (70188217)
SAOTOME MASAO 浜松医科大学, 医学部附属病院, 助教 (70509512)
URUSHIDA TSUYOSHI 浜松医科大学, 医学部, 助教 (20334980)
KATOH HIDEKI 浜松医科大学, 医学部, 助教 (80314029)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Keywords | 心腔内血流 / 左室 / 左房 / 心不全 |
Outline of Final Research Achievements |
Intra-cardiac blood flow changes under various conditions and might affect global cardiac function. In this study, by using phase-resolved 3-dimensional cine phase contrast magnetic resonance imaging (4D-Flow), vortex formation in the left atrium (LA) and the left ventricle (LV) was visualized and factors affecting the intra-cardiac flow dynamics were examined. The vortex formation in LA might depend on LV and LA volume. The intra-LV vortex during the diastolic phase was larger and located at the more apical LV in patients with impaired LV function. 4D-Flow can show the 3-dimensional alterations of intra-cardiac flow dynamics in a noninvasive and comprehensive manner.
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Free Research Field |
循環器内科学
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