Analysis of blood flow in the heart using MRI

2015 Fiscal Year Final Research Report

• Project/Area Number: 25461050
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Cardiovascular medicine
• Research Institution: Hamamatsu University School of Medicine
• Principal Investigator: SAITOH TAKEJI 浜松医科大学, 医学部附属病院, 講師 (50402277)
• Co-Investigator(Kenkyū-buntansha): SATOH HIROSHI 浜松医科大学, 医学部附属病院, 講師 (30293632) ; TAKEHARA YASUO 浜松医科大学, 医学部附属病院, 教授 (70188217) ; SAOTOME MASAO 浜松医科大学, 医学部附属病院, 助教 (70509512) ; URUSHIDA TSUYOSHI 浜松医科大学, 医学部, 助教 (20334980) ; KATOH HIDEKI 浜松医科大学, 医学部, 助教 (80314029)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 心腔内血流 / 左室 / 左房 / 心不全

Outline of Final Research Achievements

Intra-cardiac blood flow changes under various conditions and might affect global cardiac function. In this study, by using phase-resolved 3-dimensional cine phase contrast magnetic resonance imaging (4D-Flow), vortex formation in the left atrium (LA) and the left ventricle (LV) was visualized and factors affecting the intra-cardiac flow dynamics were examined. The vortex formation in LA might depend on LV and LA volume. The intra-LV vortex during the diastolic phase was larger and located at the more apical LV in patients with impaired LV function. 4D-Flow can show the 3-dimensional alterations of intra-cardiac flow dynamics in a noninvasive and comprehensive manner.

Free Research Field

循環器内科学