2015 Fiscal Year Final Research Report
Establishment of a high sensitivity measurement system for soluble angiotensin IV receptor and evaluation of the utility
| Project/Area Number |
25461245
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Kidney internal medicine
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
ZENIMARU YASUO 福井大学, 医学部附属病院, 特命助教 (20397269)
FUJII MIKI 福井大学, 医学部附属病院, 病院助教 (10401978)
IMAGAWA MICHIKO 福井大学, 医学部附属病院, 特命助教 (70464055)
ICHIKAWA MAI 福井大学, 医学部附属病院, 医員 (30646659)
YAMADA MIKA 福井大学, 医学部附属病院, 医員 (90646655)
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| Research Collaborator |
SUZUKI JINYA 医学部附属病院, 講師 (20293417)
YAMAMOTO KATSUSHI 福井大学, 医学部附属病院, 医員 (40753950)
NAKAYA TAKAHIRO 福井大学, 医学部附属病院, 医員 (50750353)
SAKAI AI 福井大学, 医学部附属病院, 医員 (40750352)
MAKINO YASUKAZU 福井大学, 医学部, 大学院生
SATO SATSUKI 福井大学, 医学部, 大学院生
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | アンジオテンシンIV受容体 / LNPEP / IRAP / レニン－アンジオテンシン系 / 高血圧 / 糖尿病 / 糖尿病性腎症 |
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| Outline of Final Research Achievements |
We had identified Angiotensin IV (AT4) receptor as a hypertension/diabetes specific gene through genetic DNA chip analysis and we had already established a measurement system for this AT4. This time we tried to improve the sensitivity of the measurement by monoclonal antibody methods and as a result we could established a next generation measurement system for AT4 with largely improved sensitivity. This measurement system would be of use for medical care of life-style related diseases.
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| Free Research Field |
医歯薬学
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