2015 Fiscal Year Final Research Report
Schizophrenia and oligodendrocyte; roles of hnRNPC1 and 2
| Project/Area Number |
25461756
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | University of Fukui |
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Principal Investigator |
Iwata Keiko 福井大学, 子どものこころの発達研究センター, 特命助教 (30415088)
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| Co-Investigator(Kenkyū-buntansha) |
MATSUZAKI Hideo 福井大学, 子どものこころの発達研究センター, 教授 (00334970)
MANABE Takayuki 中京学院大学, 看護学部, 教授 (90382283)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | oligodendrocyte / schizophrenia / hnRNPC |
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| Outline of Final Research Achievements |
The aim of this project is elucidation of pathophysiology of schizophrenia regarding myelination abnormality. We found that the expression change of hnRNP C2 effected on the expression of a myelination gene. Our findings suggest the involvement of the molecule in myelination and the pathophysiology of schizophrenia.
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| Free Research Field |
Neuroscience
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