2015 Fiscal Year Final Research Report
Increase in Abeta42 production and accelerated dissociation of Abeta42 from gamma-secretase
| Project/Area Number |
25461768
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Osaka University |
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Principal Investigator |
Okochi Masayasu 大阪大学, 医学(系)研究科(研究院), 講師 (90335357)
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| Co-Investigator(Kenkyū-buntansha) |
TAGAMI Shinji 大阪大学, 医学系研究科, 助教 (40362735)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | アルツハイマー病 |
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| Outline of Final Research Achievements |
We have analyzed long Abeta binding to gamma-secretase, and found that dissociation of long Abeta from gamma-secretase is enhanced, when Abeta42 production increases.
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| Free Research Field |
精神医学
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