Development of arterial spin labeling MRI for female pelvic organs

2015 Fiscal Year Final Research Report

• Project/Area Number: 25461806
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: University of Fukui
• Principal Investigator: KOSAKA NOBUYUKI 福井大学, 医学部, 助教 (60397247)
• Co-Investigator(Kenkyū-buntansha): KIMURA Hirohiko 福井大学, 医学部, 教授 (10242596) ; KUROKAWA Tetsuji 福井大学, 医学部, 准教授 (60334835) ; FUJIWARA Yasuhiro 熊本大学, 大学院生命科学研究部(保), 講師 (90422675) ; KANAMOTO Masayuki 福井大学, 医学部附属病院, 診療放射線技師 (60730728)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: MRI / 子宮 / 腎臓 / 灌流画像 / 放射線 / Arterial spin labeling

Outline of Final Research Achievements

In this project, we developed non-contrast enhanced perfusion MRI method (arterial spin labeling method: ASL-MRI) for abdominal organs. The tissue perfusions in kidneys measured with this ASL-MRI were validated by comparing nuclear imaging methods. Furthermore, we applied this method to placental polyps in uterus, and successfully depicted their tissue perfusions and therapeutic responses visually and semi-quantitatively. Although further technical development may be needed for more stable image acquisitions, this ASL-MRI method has clinical potential for non-invasive assessment of tissue perfusion in uterus and other abdominal organs.

Free Research Field

放射線医学