Blood flow evaluation and clinical application of the transplanted kidney by non-contrast-enhanced MR perfusion image using the ASL technique

2015 Fiscal Year Final Research Report

• Project/Area Number: 25461834
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kyushu University
• Principal Investigator: Nishimuta Yusuke 九州大学, 大学病院, その他 (10635220)
• Co-Investigator(Kenkyū-buntansha): Nishie Akihiro 九州大学, 医学研究院, 講師 (20457427) ; Fujita Nobuhiro 九州大学, 病院, 助教 (30610612) ; Yoshiura Takashi 鹿児島大学, 医学部, 教授 (40322747) ; Asayama Yoshiki 九州大学, 医学研究院, 教授 (40380414) ; Ushijima Yasuhiro 九州大学, 医学研究院, 助教 (40432934) ; Takayama Yukihisa 九州大学, 医学研究院, 助教 (60546563) ; Yamashita Koji 九州大学, 大学病院, 助教 (80546565) ; Honda Hiroshi 九州大学, 医学研究院, 教授 (90145433) ; Tsurumaru Daisuke 九州大学, 大学病院, 助教 (90419565) ; Miyasaka Mitsutoshi 九州大学, 大学病院, 助教 (10457434)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 腎血流 / MRI / ASL

Outline of Final Research Achievements

Blood flow evaluation of the transplanted kidney by non-contrast-enhanced MR perfusion image using the ASL technique

In this study, we have developed a non-contrast-enhanced MR perfusion image using the ASL method for functional assessment after renal transplantation. We used the pulsed continuous ASL (pCASL) method in this study. In healthy volunteers, good images were obtained in all cases, and it was possible to qualitatively and quantitatively evaluate the images. In patients with renal tumors, good images were also obtainable in several cases; however, it was difficult to carry out qualitative and quantitative evaluations in all cases. It is likely that blood flow signal degradation in patients with renal tumors occurs due to respiratory motion and decreased renal function; this indicates a need for an improved further sequence.

Free Research Field

放射線科学