• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2015 Fiscal Year Annual Research Report

高精度放射線治療を用いた子宮頸癌根治的放射線治療の至適線量スケジュールの開発

Research Project

Project/Area Number 25461919
Research InstitutionUniversity of the Ryukyus

Principal Investigator

戸板 孝文  琉球大学, 医学(系)研究科(研究院), 准教授 (30237036)

Co-Investigator(Kenkyū-buntansha) 粕谷 吾朗  琉球大学, 医学部附属病院, その他 (00639932) [Withdrawn]
大野 達也  群馬大学, 学内共同利用施設等, 教授 (10344061)
垣花 泰政  琉球大学, 医学(系)研究科(研究院), 助教 (20185713)
宇野 隆  千葉大学, 医学(系)研究科(研究院), 教授 (30302540)
石倉 聡  順天堂大学, 医学部, その他 (40407242)
有賀 拓郎  琉球大学, 医学部附属病院, 助教 (60647337)
Project Period (FY) 2013-04-01 – 2016-03-31
KeywordsIGBT / 臨床試験
Outline of Annual Research Achievements

昨年度に引き続き中央遮蔽なしの外部照射と3次元計画腔内照射(IGBT)併用の治療スケジュールを採用した前向き臨床試験への患者登録を進めた。平成28年3月31日まで計36例が登録された(予定40例)。年齢は34-84才(平均56才)であった。FIGO病期は、IB1: 11例、IB2: 11例、IIA2:1例、IIB: 9例、IIIB: 3例、IVA: 1例であった。MRIで計測した腫瘍最大径は13-80mm(平均43mm)で、CTにて短径10mm以上の骨盤リンパ節腫大を認めたのは15例であった。11例は放射線治療単独、25例はCCRTが行われた。観察期間1-23ヶ月で、局所再発/遺残2例、癌性腹膜炎1例を認めている。Grade 1の直腸炎を1例に認めた。登録例についてIGBTのDVHパラメータの解析を開始した。

  • Research Products

    (16 results)

All 2016 2015

All Journal Article (10 results) (of which Peer Reviewed: 5 results,  Open Access: 3 results) Presentation (5 results) (of which Int'l Joint Research: 3 results,  Invited: 4 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Proposed definition of the vaginal cuff and paracolpium clinical target volume in postoperative uterine cervical cancer.2016

    • Author(s)
      Murakami N, Norihisa Y, Isohashi F, Murofushi K, Ariga T, Kato T, Inaba K, Okamoto H, Ito Y, Toita T, Itami J.
    • Journal Title

      Pract Radiat Oncol.

      Volume: 6 Pages: 5-11

    • DOI

      10.1016/j.prro.2015.04.008.

    • Peer Reviewed
  • [Journal Article] 子宮頸癌に対する化学放射線療法の現状と今後の展望.2015

    • Author(s)
      戸板孝文、有賀拓郎、粕谷吾朗、橋本成司、前本均、平安名常一、垣花泰政、村山貞之.
    • Journal Title

      癌と化学療法.

      Volume: 42 Pages: 1156-1161

  • [Journal Article] 子宮頸がんに対する同時化学放射線療法の今後. ゲノム時代の婦人科がん診療を展望する がんの個性に応じたpersonalizationへの道.2015

    • Author(s)
      戸板孝文、粕谷吾朗、有賀拓郎.
    • Journal Title

      臨床婦人科産科

      Volume: 69 Pages: 59-62

  • [Journal Article] 腹部骨盤内臓器の有害事象 特に子宮癌術後照射について.2015

    • Author(s)
      戸板孝文、有賀拓郎、粕谷吾朗、橋本成司、前本均、平安名常一、垣花泰政、村山貞之.
    • Journal Title

      臨床放射線

      Volume: 60 Pages: 1225-1230

  • [Journal Article] A questionnaire-based survey on 3D image-guided brachytherapy for cervical cancer in Japan: advances and obstacles.2015

    • Author(s)
      Ohno T, Toita T, Tsujino K, Uchida N, Hatano K, Nishimura T, Ishikura S.
    • Journal Title

      J Radiat Res.

      Volume: 56 Pages: 897-903

    • DOI

      10.1093/jrr/rrv047.

    • Peer Reviewed / Open Access
  • [Journal Article] Treatment outcomes of patients with FIGO Stage I/II uterine cervical cancer treated with definitive radiotherapy: a multi-institutional retrospective research study.2015

    • Author(s)
      Ariga T, Toita T, Kato S, Kazumoto T, Kubozono M, Tokumaru S, Eto H, Nishimura T, Niibe Y, Nakata K, Kaneyasu Y, Nonoshita T, Uno T, Ohno T, Iwata H, Harima Y, Wada H, Yoshida K, Gomi H, Numasaki H, Teshima T, Yamada S, Nakano T.
    • Journal Title

      J Radiat Res.

      Volume: 56 Pages: 841-848

    • DOI

      10.1093/jrr/rrv036.

    • Peer Reviewed / Open Access
  • [Journal Article] A surveillance study of intensity-modulated radiation therapy for postoperative cervical cancer in Japan.2015

    • Author(s)
      Murakami N, Okamoto H, Isohashi F, Murofushi K, Ohno T, Yoshida D, Saito M, Inaba K, Ito Y, Toita T, Itami J.
    • Journal Title

      J Radiat Res.

      Volume: 56 Pages: 735-741

    • DOI

      10.1093/jrr/rrv020.

    • Peer Reviewed / Open Access
  • [Journal Article] 子宮頸がん臨床試験の最前線. GCIG 2014 Cervical Cancer Brainstorming Meeting in Melbourneの報告(1)2015

    • Author(s)
      寒河江悟、戸板孝文、三上幹男、岡本愛光、万代昌紀、落合和徳.
    • Journal Title

      産婦人科の実際

      Volume: 64 Pages: 549-554

  • [Journal Article] 子宮頸がん臨床試験の最前線. GCIG 2014 Cervical Cancer Brainstorming Meeting in Melbourneの報告(2).2015

    • Author(s)
      寒河江悟、戸板孝文、三上幹男、岡本愛光、万代昌紀、落合和徳.
    • Journal Title

      産婦人科の実際

      Volume: 64 Pages: 705-711

  • [Journal Article] Concurrent use of strontium-89 with external beam radiotherapy for multiple bone metastases: early experience.2015

    • Author(s)
      Heianna J, Toita T, Endo W, Kasuya G, Ariga T, Hashimoto S, Maemoto H, Terui K, Miura N, Togashi A, Miyauchi T, Murayama S.
    • Journal Title

      Ann Nucl Med.

      Volume: 29 Pages: 848-853

    • DOI

      10.1007/s12149-015-1010-6.

    • Peer Reviewed
  • [Presentation] Current status of IMRT for cervical cancer. Symposium 5- Radiation Oncology2015

    • Author(s)
      Toita T, Murakami N, Isohashi F, Okamoto H, Hasumi Y, Kasamatsu T.
    • Organizer
      The 4th Biennial Meeting of Asian Society of Gynecologic Oncology.
    • Place of Presentation
      Lotte Hotel Seoul, Korea
    • Year and Date
      2015-11-14
    • Int'l Joint Research / Invited
  • [Presentation] 子宮頸癌ガイドライン:放射線治療に関する記述の問題点と課題.2015

    • Author(s)
      戸板孝文
    • Organizer
      第57回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      アイーナいわて県民情報交流センター、盛岡、岩手県
    • Year and Date
      2015-08-07 – 2015-08-09
    • Invited
  • [Presentation] Chemoradiotherapy for uterine cervical cancer. Radiation Oncology Update: Chemoradiotherapy.2015

    • Author(s)
      Toita T.
    • Organizer
      The 15th International Congress of Radiation Research.
    • Place of Presentation
      Kyoto International Conference Center, Kyoto, Sakyo-ku)
    • Year and Date
      2015-05-27
    • Int'l Joint Research / Invited
  • [Presentation] Roles and perspectives of photon beam radiotherapy (RT) in the next era of particle RT: the personal opinions of a radiation oncologist in Okinawa.2015

    • Author(s)
      Toita T
    • Organizer
      OIST mini symposium “New Medical Imaging and Advanced Cancer Therapy (BNCT) Instrumentation”
    • Place of Presentation
      OIST (Okinawa Institute of Science and Technology Graduate University) Seaside House, Onna, Okinawa
    • Year and Date
      2015-05-16
    • Int'l Joint Research / Invited
  • [Presentation] The efficacy and safety of estrogen drug administration during definitive radiotherapy for postmenoposal patients with uterine cervical cancer.2015

    • Author(s)
      Kasuya G, Toita T, Nagai Y, Ariga T, Hashimoto S, Heianna J, Murayama S.
    • Organizer
      The 74th Annual Meeting of the Japan Radiological Society
    • Place of Presentation
      PACIFICO Yokohama, Yokohama, Kanagawa
    • Year and Date
      2015-04-16 – 2015-04-19
  • [Patent(Industrial Property Rights)] 患者移送用寝台及び患者移送システム2016

    • Inventor(s)
      戸板孝文
    • Industrial Property Rights Holder
      戸板孝文
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      特願2013-084407
    • Filing Date
      2016-03-23

URL: 

Published: 2017-01-06  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi