An innovative new endoscopic surgical system using fluorescent measurement technology for gastroenterological operation

2015 Fiscal Year Final Research Report

• Project/Area Number: 25462009
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Digestive surgery
• Research Institution: Tohoku University
• Principal Investigator: KAMEI TAKASHI 東北大学, 医学(系)研究科(研究院), 准教授 (10436115)
• Co-Investigator(Kenkyū-buntansha): NAKAGAWA TOMOHIKO 東北大学, 病院, 医員 (00646804) ; GONDA KOUSUKE 東北大学, 大学院医学系研究科, 教授 (80375435) ; Ohuchi Noriaki 東北大学, 大学院医学系研究科, 教授 (90203710) ; TESHIMA JIN 東北大学, 病院, 医員 (90579749)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 蛍光プロ―ブ / 蛍光内視鏡手術 / 蛍光クリップ / リアルタイムナビゲーション

Outline of Final Research Achievements

The aim of this research was development of a new fluorescent endoscopic surgical system and we had the study results as below.
1.We created an original organic fluorescent probe and analyzed the property of this particle. This probe had advantages in fluorescent signal intensity and degradation time compared with quantum dot or ICG.2.We developed an original gastrointestinal endoscopic clip with the new fluorescent probe. 3.We developed an original fluorescent endoscopic surgical system and refined the conditions for human application in the future.4.We successfully detected the fluorescent signal of the clips from outside of the gastrointestinal tract in pig model using our original surgical system.5.We performed analysis of the fluorescent property and dynamics of the original fluorescent particle in living tissues.

Free Research Field

消化器外科