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2015 Fiscal Year Final Research Report

Novel intraoperative monitoring using near- infrared spectroscopy-visualization of cortico-cortical network system

Research Project

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Project/Area Number 25462246
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Neurosurgery
Research InstitutionNiigata University

Principal Investigator

Fukuda Masafumi  新潟大学, 脳研究所, 非常勤講師 (00361907)

Co-Investigator(Kenkyū-buntansha) AOKI Hiroshi  新潟大学, 脳研究所, 非常勤講師 (30515771)
Research Collaborator TAKAO Tetsuro  
HIRAISHI Tetsuya  
SATO Keisuke  
SATO Yosuke  
Project Period (FY) 2013-04-01 – 2016-03-31
KeywordsNIRS / cortico-cortical network / imonitoring / cortical stimulation / epilepsy surgery
Outline of Final Research Achievements

We developed novel probes of near-infrared spectroscopy (NIRS) to measure regional cerebral blood flow (rCBF) from brain surfaces. In a patient with brain tumor, stimulation to the supplementary motor area, where the seizure onset zone existed, lead to increase in rCBF in the primary motor area by intraoperative NIRS. In the other patients with brain tumor, stimulation to the inferior frontal gyrus in the left side resulted in increase in rCBF in the superior temporal gyrus. These results suggest that intraoperative NIRS could visualize cortico-cortical network system. In future, intraoperative NIRS likely evaluates the language system as intraopeartive monitoring.

Free Research Field

機能的脳神経外科

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Published: 2017-05-10  

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