2015 Fiscal Year Final Research Report
Novel intraoperative monitoring using near- infrared spectroscopy-visualization of cortico-cortical network system
| Project/Area Number |
25462246
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neurosurgery
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
AOKI Hiroshi 新潟大学, 脳研究所, 非常勤講師 (30515771)
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| Research Collaborator |
TAKAO Tetsuro
HIRAISHI Tetsuya
SATO Keisuke
SATO Yosuke
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | NIRS / cortico-cortical network / imonitoring / cortical stimulation / epilepsy surgery |
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| Outline of Final Research Achievements |
We developed novel probes of near-infrared spectroscopy (NIRS) to measure regional cerebral blood flow (rCBF) from brain surfaces. In a patient with brain tumor, stimulation to the supplementary motor area, where the seizure onset zone existed, lead to increase in rCBF in the primary motor area by intraoperative NIRS. In the other patients with brain tumor, stimulation to the inferior frontal gyrus in the left side resulted in increase in rCBF in the superior temporal gyrus. These results suggest that intraoperative NIRS could visualize cortico-cortical network system. In future, intraoperative NIRS likely evaluates the language system as intraopeartive monitoring.
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| Free Research Field |
機能的脳神経外科
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