2016 Fiscal Year Final Research Report
Biomarker profiles of perioperative acute lung injury
Project/Area Number |
25462427
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Anesthesiology
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Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
Mamoru Yamamoto 東京医科歯科大学, 医学部附属病院, 助教 (90422477)
|
Project Period (FY) |
2013-04-01 – 2017-03-31
|
Keywords | バイオマーカー / 急性肺傷害 |
Outline of Final Research Achievements |
In this study, we measured serum levels of interleukin-8 and angiopoietin-II in (1) 80 patients undergoing elective cardiac surgery, and (2) 70 patients undergoing lung surgery. We showed that serum levels of angiopoietin-II elevated up to POD-1 whereas interleukin-8 levels peaked immediately after surgery in these two study cohorts. In the lung surgery study, the serum levels of these two biomarkers were significantly higher in patients undergoing pleurectomy/decortication, than those in patients undergoing lobectomy.
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Free Research Field |
麻酔科学
|