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2015 Fiscal Year Final Research Report

The mechanisum and effect of dorsal root ganglion pulsed radiofrequency on responses of nerve fibers

Research Project

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Project/Area Number 25462455
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Anesthesiology
Research InstitutionAichi Medical University

Principal Investigator

Arai Young-Chang  愛知医科大学, 医学部, 准教授 (50380316)

Co-Investigator(Renkei-kenkyūsha) Nishihara Makoto  愛知医科大学, 医学部, 教授 (60380325)
Ushida Takahiro  愛知医科大学, 医学部, 教授 (60304680)
Project Period (FY) 2013-04-01 – 2016-03-31
Keywordsパルス高周波法神経根ブロック / A-δ線維 / 鎮痛メカニズム
Outline of Final Research Achievements

Not only dorsal root ganglion pulsed radiofrequency but also intravenous magnesium and lidocaine have been used for the management of intractable pain individually or in combination and a study reported the sound effect of the intravenous combination on neuralgia when antiepileptic drugs failed. One of the aims is to see how a combination of intravenous magnesium and lidocaine influenced electrically-evoked responses of peripheral A-δ and A-β nerve fibers at non-affected and affected areas. Although three patients with neuralgia experienced sound pain relief, the combination had a different effect on peripheral A-δ and A-β nerve fibers at non-affected and affected areas in each patient. The second aim is to see how dorsal root ganglion pulsed radiofrequency influenced peripheral A-δ and A-β nerve fibers at non-affected and affected areas in patients with vertebral metastatic pain. Now, the number of the study sample has been increasing.

Free Research Field

疼痛管理

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Published: 2017-05-10  

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