the development of revitalization methods on kidney grafting from cardiac death donors

2016 Fiscal Year Final Research Report

• Project/Area Number: 25462543
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Urology
• Research Institution: Kitasato University
• Principal Investigator: IWAI SATOMI 北里大学, 獣医学部, 講師 (30566542)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 腎移植 / マージナル腎 / 常温保存 / 間葉系幹細胞

Outline of Final Research Achievements

Normothermic preservation with an extracellular-type solution was　beneficial for the short-term storage of a marginal kidney(Iwai S. et al. PLoS One. 2012;7(3):e33157.). This approach will be able to extend the preservation period of marginal kidneys or to provide improved function of marginal kidneys for longer periods. Mesenchymal stem cells (MSC) treatment was improved compared with that in the MSC nontreatment group. Local injection of MSC is a potentially safer route of administration than is high-dosage, intravenous injection(Iwai S. et al. Transplantation proceedings, 2014;46:1578-84.).

Free Research Field

腎移植