2015 Fiscal Year Final Research Report
Development of treatment strategy for age-related decline in oocyte quality by analyzing lipid metabolism
| Project/Area Number |
25462550
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Yamagata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TSUTSUMI Seiji 山形大学, 医学部, 講師 (50323168)
IGARASHI Hideki 山形大学, 医学部, 助教 (80333970)
HARA Shuichiro 山形大学, 医学部, 助教 (10436230)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 卵の加齢 / リピドミクス / ミトコンドリア / ベータ酸化 / 脂肪酸 |
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| Outline of Final Research Achievements |
The age-associated decline in female fertility is largely attributable to the decrease in oocyte quality due to ovarian aging. However, the precise mechanisms of oocyte aging due to ovarian aging remain unknown. In the present study, we examined the molecular mechanisms of age-related decline in oocyte quality by analyzing lipid metabolism.
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| Free Research Field |
医歯薬学
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