2015 Fiscal Year Final Research Report
cancer-related small RNA as a biomarker for head and neck cancer
| Project/Area Number |
25462691
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kyorin University (2015)
Keio University (2013-2014) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
IWAMARU Arifumi 慶應義塾大学, 医学部, 研究員 (00296592)
ZAMA Takeru 慶應義塾大学, 医学部, 特任講師 (30296719)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 頭頸部癌 / 診断 / 治療 |
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| Outline of Final Research Achievements |
In this study, we have found that miR-196a could be a potential diagnostic biomarker for laryngeal cancer. Furthermore, results of our study suggested that this miR could be a promising future diagnostic target to treat laryngeal cancer.
Furthermore, we have investigated the human papillomvirus (HPV) expression in laryngeal papilloma. We found expressions of several unique HPV subtypes in laryngeal papilloma tissues. We further assessed the HPV subtypes combined with our abundant clinical background data of the patients, and found several promising findings. These unique and promising results offered multiple opportunities for us to present our data in Japan and US.
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| Free Research Field |
喉頭科学
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