The analysis of retinal morphological change and visual function using adaptive optics fundus imaging device and focal macular electroretinogram

2015 Fiscal Year Final Research Report

• Project/Area Number: 25462710
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Nagoya University
• Principal Investigator: Ito Yasuki 名古屋大学, 医学(系)研究科(研究院), 准教授 (10313991)
• Co-Investigator(Kenkyū-buntansha): Terasaki Hiroko 名古屋大学, 大学院医学系研究科, 教授 (40207478)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 補償光学眼底撮影装置 / 光干渉断層計 / 黄斑部局所網膜電図 / 視細胞 / 網膜血管

Outline of Final Research Achievements

In this study, fine retinal findings were analyzed using optical coherence tomography, adaptive optics fundus imaging device (AO), and focal macular electroretinogram (FMERG). The method to measure the cone density using automacic counting software with the manual correction for the reproducible measurement was investigated. It was shown that the amplitude of the FMERG were associated with the cone density. In the vascular imaging using AO, the method to visualize retinal artery wall and neovascular vessels in the eyes with proliferative diabetic retinopathy using offset mode of AO-scanning laser ophthalmoscope were investigated. Recovery of cone cell density in eyes after retinal detachment surgery and the decrease of the cone density in eyes with occult macular dystrophy were also investigated.

Free Research Field

眼科学