2015 Fiscal Year Final Research Report
Development of novel device for ocular surface treatment with tranparent amnion membrane
| Project/Area Number |
25462748
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA YUJI 国立研究開発法人理化学研究所, 情報基盤センター, 常任研究員 (40625513)
WATANABE RYO 東北大学, 大学院医学系研究科, 非常勤講師 (70625293)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 透明化積層化羊膜 / 組織工学 |
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| Outline of Final Research Achievements |
We made alternative corneal stroma having strenght and tranparency the same as normal corneal stroma with transparent human amniotic membrane laminates. When these laminates were tranplanted to rabbit cornea, these membranes survived for a long time. These laminates were useful for filling scleral defect and covering glaucoma shunt device. We manipulated scleral contact lens with these laminates. When this contact lens was worn on chemical injured rabbit cornea, inflammation on the ocular surface was reduced significantly. This contact lens might be effective for severe ocular surface inflammation.
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| Free Research Field |
眼科学
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