2016 Fiscal Year Final Research Report
the role of versican in skin and wound healing
| Project/Area Number |
25462801
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Keio University |
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Principal Investigator |
Aramaki Noriko 慶應義塾大学, 医学部(信濃町), 講師 (80365311)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | versican / wound healing / scarless wound |
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| Outline of Final Research Achievements |
In a wound-healing model using Vcanhdf/+ mice, we found that neovascularization is more strongly suppressed in Vcanhdf/+ mice than WT mice.This same phenomenon was observed using the cancer model in this study, suggesting that versican may have an important role in neovascularization. In the future, we plan to conduct functional analyses of versican on neovascularization.
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| Free Research Field |
形成外科
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