2015 Fiscal Year Final Research Report
Evaluation of the in vitro bioactivity of a prototype tricalcium silicate cement
| Project/Area Number |
25462954
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Conservative dentistry
|
|---|
| Research Institution | Niigata University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
Okiji Takashi 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (80204098)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Keywords | ケイ酸カルシウム / 歯内療法 / 覆髄 / リン酸カルシウム / アパタイト / MTA / PBS / CS |
|---|
| Outline of Final Research Achievements |
To evaluate the Ca2+-releasing, alkalizing, and apatite-like surface precipitate-forming abilities of a prototype tricalcium silicate cement. The chemical compositions were analyzed with EPMA. The pH and Ca2+ concentrations immersed were measured. The surface precipitates formed on the materials immersed in PBS were analyzed with EPMA and XRD. The prototype cement contained Ca, Si, and Zr as major elemental constituents, whereas it did not contain some metal elements that were detected in the other materials. The Ca2+ concentrations and pH of the immersion water samples exhibited the following order: WMTA = prototype cement > TheraCal LC (P <0.05). XRD peaks corresponding to hydroxyapatite were detected in the precipitates produced by the prototype cement and WMTA. The prototype tricalcium silicate cement exhibited similar Ca2+-releasing, alkalizing, and apatite-like precipitate-forming abilities to WMTA.
|
| Free Research Field |
生体材料
|
